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Stins do not have a desired effect for half the patients, study finds Association



About half of patients with prescribed statins do not see the drop of cholesterol to desired levels within two years, new research suggests

The National Institute for Health and Care Excellence ( Nice) 40% or more reduced in low-density lipoprotein cholesterol from the treatment.

As a result of a new study, published in the Heart magazine, half of the people (51%) received a “sub-optimal” response after 24 months of the drugs.

The researchers, from the University of Nottingham, analyzed data from 1

65,411 patients who were given statins in primary care between 1990 and 2016.

They were 62 years of age on average when they began treatment .

A total of 84,609 patients responded “sub-optimal” after two years and did not record a cholesterol reduction of 40% or more.

The researchers noted that lower strength offenses were prescribed by a higher percentage of patients with an “optimal” response co

Patients who had not received targeted levels 22% were more likely to develop cardiovascular disease than they were. those who responded well, got the study.

The researchers said that the

study provides “the results of this contribute to the debate on the effectiveness of statin therapy and highlight the need for personal medicine in lipid management for patients,” they wrote.

Professor Metin Avkiran, associate medical director of the British Heart Foundation said: “Statites are an important and proven treatment for lowering cholesterol and the risk of a potentially fatal heart attack or stroke. reduction. reduce their cholesterol adequately, it does not explain why.

“These people may have low-dose or low-power stats, they are coming without taking the medication as it is prescribed, or they are not responding well to the type of statins were prescribed.

“If you have prescribed statins you should continue to take them regularly, as prescribed.

“If you have any concerns you should discuss your medication with your family doctor

Professor Helen Stokes-Lampard, chair of the Royal College of General Practitioners, said:“ When we prescribe medication, we have to be rely on patients to make sure they take it, at the recommended dose and for the period we think will benefit them most.

“There is a lot of research showing that most people are safe and effective drugs, and that they can reduce the risk of heart attacks and strokes, when properly prescribed – but there is always controversy about their use and their potential consequences.

“There are complex reasons that patients choose not to take their prescribed medication, and one of these may have messages around statins. ”


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